Journal
NEWS IN PHYSIOLOGICAL SCIENCES
Volume 18, Issue -, Pages 119-124Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/nips.01434.2003
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Proteins of the FXYD family act as tissue-specific regulators of the Na-K-ATPase. They are small hydrophobic type I proteins with a single-transmembrane span containing an extracellular invariant FXYD sequence. FXYD proteins are not an integral part of the Na-K-ATPase but function to modulate its catalytic properties by molecular interactions with specific Na-K-ATPase domains.
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