Journal
NUTRITION REVIEWS
Volume 61, Issue 6, Pages 189-203Publisher
OXFORD UNIV PRESS INC
DOI: 10.1301/nr.2003.jun.189-203
Keywords
soy; isoflavones; phytoestrogens; cholesterol; triglycerides; cardiovascular disease risk
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Epidemiologic data suggest an inverse relationship between the consumption of soy isoflavones and cardiovascular disease risk. The aims of this review are to determine if isoflavones play a role in the hypocholesterolemic effect of soy and whether the studies realized with that scope were adequately designed. In humans, Most studies have been performed in postmenopausal women., The results are inconsistent, however; some studies show a decrease in total cholesterol and low-density lipo protein concentrations, and an increase in high-density lipoprotein levels, and other investigations fail to show any beneficial effect of soy isoflavones on lipid profiles. In most studies, beneficial effects could not be attributed with certainty to soy isoflavones. If these components have any health-protecting effect in humans, it is small in comparison with the effect of soy protein itself. There are currently not enough data to recommend the consumption of isoflavone supplements to lower plasma cholesterol levels.
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