Journal
NEUROPSYCHOLOGY REVIEW
Volume 13, Issue 2, Pages 79-92Publisher
SPRINGER
DOI: 10.1023/A:1023832305702
Keywords
Alzheimer's disease; disconnection; neuropsychology
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This paper reviews the growing amount of evidence supporting the hypothesis that Alzheimer's disease includes a disconnection syndrome. This evidence came mainly from neuropathological, electrophysiological, and neuroimaging studies. Moreover, a few recent neuropsychological studies have also explored the effects of a disconnection between cerebral areas on cognitive functioning. Finally, and more generally, the contribution of this interpretation to the understanding of Alzheimer's disease cognitive deficits is considered.
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