Journal
MOLECULAR DIVERSITY
Volume 7, Issue 2-4, Pages 273-280Publisher
SPRINGER
DOI: 10.1023/B:MODI.0000006860.56083.2b
Keywords
heterocyclic chemistry; large scale; microwave chemistry
Categories
Funding
- CEM Corporation
- PFIZER
- 'Comite de Charente Maritime de la Ligue Nationale Contre le Cancer'
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The interest of microwaves in drug discovery and multi-step synthesis is exposed with the aim of describing our strategy. These studies are connected with our work on the synthesis of original heterocyclic compounds with potential pharmaceutical value. Reactions in the presence of solvent and solvent-free synthesis can be realised under a variety of conditions; for some of these selected results are given, and where available, results from comparison with the same solvent-free conditions but with classical heating are given.
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