4.7 Review

Inflammation Imaging in Atherosclerosis

Journal

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Volume 29, Issue 7, Pages 1009-1016

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/ATVBAHA.108.165563

Keywords

pathophysiology; imaging; computed tomography and magnetic resonance imaging; nuclear cardiology and positron-emission tomography; cardiovascular imaging agents/techniques

Funding

  1. British Heart Foundation
  2. NIHR Cambridge Biomedical Research Centre
  3. Federation Francaise de Cardiologie
  4. NIH/NHLBI [R01 HL071021, R01 HL078667]
  5. Academy of Medical Sciences (AMS) [AMS-SGCL1-Rudd] Funding Source: researchfish

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Inflammation is important at many stages of atherosclerotic plaque development. We highlight several imaging modalities that can quantify the degree of plaque inflammation noninvasively. Imaging of this type might allow testing of novel antiatherosclerosis drugs, identification of patients at risk of plaque rupture, and deeper insight into the biology of the disease. The imaging modalities are discussed in relation to their potential use in these areas. (Arterioscler Thromb Vasc Biol. 2009; 29: 1009-1016.)

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