Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 7, Issue 3, Pages 362-373Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S1367-5931(03)00052-8
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The use of appropriate combinations of polymer-supported reagents, catalysts and/or scavengers is a powerful approach, both for the synthesis of single organic compounds and for parallel syntheses. A further stage of development is the use of such reactants in flow systems. So far, it has been shown that a variety of flow formats afford excellent chemical yields and, where relevant, excellent enantiomeric excesses. The supports have a longer lifetime than in batch systems. 'Flow cascades' promise to be important in future.
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