3.8 Review

Nitric oxide and physiologic vasodilation in human limbs: Where do we go from here?

Publisher

HUMAN KINETICS PUBL INC
DOI: 10.1139/h03-035

Keywords

skin bloodflow; reactive hyperemia; exercise hyperemia; mental stress

Funding

  1. NCRR NIH HHS [RR00585] Funding Source: Medline
  2. NHLBI NIH HHS [HL 46493] Funding Source: Medline
  3. NINDS NIH HHS [NS32352] Funding Source: Medline

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This brief review highlights human studies on the role of nitric oxide (NO) and limb vasodilation conducted at the Mayo Clinic over the last 10 years. These studies have attempted to determine whether NO is responsible for the unexplained limb vasodilation seen with body heating, limb ischemia, exercise, and mental stress. Our findings are placed in context with data from others, and possible future areas of study are identified.

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