Journal
CURRENT OPINION IN NEUROBIOLOGY
Volume 13, Issue 3, Pages 341-347Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-4388(03)00064-3
Keywords
-
Categories
Ask authors/readers for more resources
Fast synaptic inhibition in the brain is largely mediated by GABA(A) receptors. These ligand-gated ion channels are crucial in the control of cell and network activity. Therefore, modulating their function or cell surface stability will have major consequences for neuronal excitation. It has become clear that the stability and activity of GABAA receptors at synapses can be dynamically modulated by receptor trafficking and phosphorylation. Here, we discuss these regulatory mechanisms, and their consequences for the efficacy of GABAA receptor mediated synaptic inhibition.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available