4.1 Article

Spontaneous anaplasia in pilocytic astrocytoma of cerebellum

Journal

BRITISH JOURNAL OF NEUROSURGERY
Volume 17, Issue 3, Pages 250-252

Publisher

CARFAX PUBLISHING
DOI: 10.1080/0268869031000153152

Keywords

astrocytoma; anaplastic astrocytoma; brain tumours; cerebellum; flow cytometry; pilocytic astrocytoma

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We report a cystic cerebellar astrocytoma with a mural nodule that contained an additional focus of astrocytoma with the histological features of anaplasia, and showed up to 48% of aneuploid and 3% S-phase cells on flow cytometry. This focus was detectable on the enhanced, as well as non-enhanced T1 and T2 images. This appears to be the first case of pilocytic astrocytoma of cerebellum with focal anaplasia detected on histological and radiological studies.

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