Journal
NATURE REVIEWS IMMUNOLOGY
Volume 3, Issue 6, Pages 454-462Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nri1111
Keywords
-
Categories
Ask authors/readers for more resources
The search for cell-surface markers that can distinguish T helper 1 (T(H)1) cells from T(H)2 cells has led to the identification of a new gene family, encoding the T-cell immunoglobulin mucin (TIM) proteins, some of which are differentially expressed by T(H)1 and T(H)2 cells. The role of the TIM-family proteins in immune regulation is just beginning to emerge. Here, we describe the various TIM-family members in mice and humans, and discuss the genetic and functional evidence for their role in regulating autoimmune and allergic diseases.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available