Journal
CURRENT OPINION IN GENETICS & DEVELOPMENT
Volume 13, Issue 3, Pages 284-289Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-437X(03)00059-5
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Funding
- NIAID NIH HHS [AI46374] Funding Source: Medline
- NIAMS NIH HHS [AR39892, AR45584] Funding Source: Medline
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Disorders of pigmentation were among the first genetic diseases ever recognized because of their visually striking clinical phenotypes, resulting from defects of pigmentary melanocytes. Recent years have seen remarkable progress in understanding these diseases, largely as a result of the systematic parallel study of human patients and inbred mice with similar phenotypes. Our understanding of disorders of pigmentation indicates that these diseases may be most usefully considered as abnormalities of melanocyte development, function, or survival.
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