Journal
JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY
Volume 49, Issue 3, Pages 141-154Publisher
MICROBIOL RES FOUNDATION
DOI: 10.2323/jgam.49.141
Keywords
actinobacteria; isolation of actinomycetes; new microorganisms; novel bioactive metabolites
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In order to facilitate the discovery of novel bioactive compounds from microorganisms, various techniques for isolation of new actinomycete strains have been attempted. Studies of the vertical distribution of actinomycetes in soil, isolation of actinomycetes from desert soils or fallen leaves, selective isolation of Kitasatospora strains using novobiocin or Actinoplanes strains using the chemotactic method, and the use of gellan gum as a solidifying agent were carried out. We discovered 9 novel bioactive compounds from actinomycete strains isolated under unusual conditions, and proposed two new genera, five new species and one new subspecies.
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