Journal
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
Volume 206, Issue 3, Pages 217-221Publisher
ELSEVIER GMBH, URBAN & FISCHER VERLAG
DOI: 10.1078/1438-4639-00217
Keywords
Evodia rutaecarpa; grape kernel extract; mastic; thyme; bactericidal activity
Ask authors/readers for more resources
The antimicrobial activity of total herbal extracts has been investigated. The MIC of extracts of Evodia rutaecarpa and grape kernel ranged between 0.25 and 1 mg/ml against gram-positive cocci and P. aeruginosa. Cocci were killed after 30-90 min of incubation in grape kernel extract (0.5 - 1.5 mg/ml), and after 8 h in evodia extract (0.5 - 1 mg/ml), respectively. C. albicans was only susceptible to evodia (MIC 0.5 mg/ml). The organic solvents of the preparations contributed to the antibacterial effect of herbal extracts with MICs of ethanol between 4 and 10 vol% and those of methanol between 6 and 10 vol%. Taking this into consideration, mastic and thyme extracts exerted hardly any microbicidal activity, while grape kernel extract and evodia were still effective at 2- to 6-fold dilutions below the MIC of the solvent. Because of the weak antimicrobial activity of total herbal extracts we recommend to give preference to preparations of single or more purified compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available