4.4 Article

Efficient one-pot synthesis of anti HIV and antitumor compounds: harman and substituted harmans

Journal

TETRAHEDRON LETTERS
Volume 44, Issue 25, Pages 4761-4763

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(03)01046-3

Keywords

harman; harmine; beta-carboline; electrocyclisation

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Anti HIV and antitumor compounds, harman and substituted harmans have been synthesized using electrocyclization reactions as key steps. A one-pot reaction sequence was used to furnish these compounds in good overall yield. (C) 2003 Elsevier Science Ltd. All rights reserved.

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