Structural studies of N-2-(6-aminopyridine)-N′-arylthioureas

N-2-(6-aminopyridine)-N'-2-methoxyphenylthiourea, 6AmTu2OMe, monoclinic, C2/c, a = 16.3150(17), b = 11.3000(13), c = 14.8970(9) Angstrom, beta = 101.219(7)degrees, V = 2693.9(4) Angstrom(3) and Z = 8; N-2-(6-aminopyridine)-N'-4-chlorophenylthiourea, 6AmTu4Cl, monoclinic, P2(1)/n, a = 14.2080(9), b = 9.8060(7), c = 19.041(1) Angstrom, beta = 104.616(4)degrees, V = 2567.0(3) Angstrom(3) and Z = 8 and N-2-(6-aminopyridine)-N'-4-nitrophenylthiourea, 6AmTu4NO(2), monoclinic, P2(1)/n, a = 10.809(8), b = 10.427(8), c = 12.303(7) Angstrom, beta = 110.47(7)degrees, V = 1299.1(16) Angstrom(3) and Z = 4. The intramolecular hydrogen bonding common to 2-pyridylthioureas between NH and the pyridine nitrogen is present as well as the intermolecular hydrogen bonding involving the thione sulfur and the N'H hydrogen, which is often found for thioureas. In addition, the presence of an amino group in the 6-position of the pyridine ring results in additional intermolecular hydrogen bonding as do the functional groups on the aryl ring of these thioureas. (C) 2003 Elsevier Science B.V. All rights reserved.