4.8 Article

Chemoselective building blocks for dendrimers from relative reactivity data

Journal

ORGANIC LETTERS
Volume 5, Issue 13, Pages 2359-2361

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0347491

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Funding

  1. NIGMS NIH HHS [GM 08523, GM 65460] Funding Source: Medline

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[GRAPHICS] Competition reactions for the substitution of monochlorotriazines with different amines provide relative reactivity data that can be used to identify new groups for the chemoselective syntheses of dendrimers; based on melamine. Target 1 is prepared using a one-pot per generation strategy without protecting group manipulations or functional group interconversions.

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