Journal
BIOCHEMISTRY
Volume 42, Issue 25, Pages 7637-7647Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bi0345079
Keywords
-
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BBS/E/J/000C0618] Funding Source: Medline
Ask authors/readers for more resources
Recently, carbohydrates have come to the fore because of their central role in many biological processes. One area of current interest concerns the enzymatic modification of sugar nucleotides, in relation to both secondary metabolite glycosylation and the formation of complex cell surface-associated glycoconjugates. Bacteria, in particular, have proven to be a rich field in which to study these transformations, because they are often unique to specific classes of organisms. This has led to the realization that such microbial biosynthetic pathways might be exploited in the generation of novel antibiotics, or indeed serve as targets for such compounds. This work illustrates the interplay between protein structure determination, chemistry, and molecular biology in providing insight into the mechanism of such biochemical transformations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available