Journal
TRENDS IN NEUROSCIENCES
Volume 26, Issue 7, Pages 337-339Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/S0166-2236(03)00143-7
Keywords
-
Categories
Ask authors/readers for more resources
The prion protein (PrP) is involved in causing a group of diverse transmissible, heritable and sporadically occurring neurodegenerative diseases. Although the identity, nature and replication of the transmissible agent have been intensely studied for decades, the cellular events underlying neuronal dysfunction and death have received comparatively little attention. Recent studies examining the occurrence and consequences of inappropriate cytoplasmic expression of the normally cell-surface PrP underscore an emerging role for PrP trafficking in prion disease pathogenesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available