Journal
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
Volume 63, Issue 3, Pages 169-179Publisher
SPRINGER BASEL AG
DOI: 10.1007/s00005-014-0324-8
Keywords
Transmission-blocking vaccine; Anti-vector vaccine; Ixodes; Dermacentor; Amblyomma; Haemaphysalis; Rhipicephalus; Ornithodoros species
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Funding
- National Institute of Health [AI090197, AI092156]
- Old Dominion University
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Tick-borne diseases are a potential threat that account for significant morbidity and mortality in human population worldwide. Vaccines are not available to treat several of the tick-borne diseases. With the emergence and resurgence of several tick-borne diseases, emphasis on the development of transmission-blocking vaccines remains increasing. In this review, we provide a snap shot on some of the potential candidates for the development of anti-vector vaccines (a form of transmission-blocking vaccines) against wide range of hard and soft ticks that include Ixodes, Haemaphysalis, Dermacentor, Amblyomma, Rhipicephalus and Ornithodoros species.
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