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Immunotherapy of Rheumatoid Arthritis Targeting Inflammatory Cytokines and Autoreactive T Cells

Journal

Publisher

SPRINGER BASEL AG
DOI: 10.1007/s00005-009-0058-1

Keywords

Rheumatoid arthritis; Immunotherapy; Inflammatory cytokines; Autoreactive T cells; Regulatory T cells; Th17 cells

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Funding

  1. Shanghai commission of Science and Technology (Shanghai Nature Science Foundation [07ZR14066, 08ZR1416100]
  2. NSFC [30972743]
  3. Shanghai Board of Health Foundation [2007126]
  4. Shanghai Institute of Immunology [08-A08]
  5. Shanghai Municipal Education Commission [09YZ104, J50207]

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Rheumatoid arthritis is a chronic disorder for which there is no known cure. Concentrating on specific elements of the abnormal immune response that characterizes the disease, scientists are reaching into biotechnology's bag of tricks to develop immunotherapeutic techniques. This paper will present some advances in the immunotherapy of rheumatoid arthritis targeting inflammatory cytokines and autoreactive T cells.

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