Nickel boride mediated reductive desulfurization of 2-thioxo-4(3H)-quinazolinones:: A new synthesis of quinazolin-4(3H)-ones and 2,3-dihydro-4(1H)-quinazolinones

A novel one-pot approach for the synthesis of aryl substituted quinazolin-4(3H) -ones and 2,3-dihydro-4(1H)-quinazolinones has been reported based on the reductive desulfurization of 3-aryl-2-thioxo-4(3H)quinazolinones with nickel boride in dry methanol at ambient temperature.