Journal
ARCHIVOS DE BRONCONEUMOLOGIA
Volume 50, Issue 7, Pages 301-304Publisher
EDICIONES DOYMA S A
DOI: 10.1016/j.arbres.2013.08.006
Keywords
Embolism; Hereditary hemorrhagic telangiectasia; Pulmonary arteriovenous malformation; Stroke
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Patients with hereditary hemorrhagic telangiectasia (HHT) and pulmonary arteriovenous malformation (PAVM) face higher risk of embolic complications. It is not clear whether poor outcomes are related to PAVM severity or pulmonary symptoms. Furthermore, there is currently no available data on HI-IT patients in Argentina. We conducted a cross sectional study in a teaching hospital in Buenos Aires, Argentina. We describe baseline characteristics of HHT and compare the prevalence of embolic complications in patients with significant PAVM compared to patients without significant PAVM. One hundred and eight consecutive patients were included. Significant PAVM was defined as: contrast echocardiography grade 2 or greater; bilateral PAVM or feeding artery bigger than 3 mm; or previous PAVM treatment. Primary composite outcome was defined as: cerebrovascular accident, cerebral abscess or peripheral embolism. 20% of participants had embolic complications, the most frequent one was stroke. Embolic complications were associated with significant PAVM and respiratory symptoms. (C) 2013 SEPAR. Published by Elsevier Espana, S.L. All rights reserved.
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