Journal
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
Volume 67, Issue 7, Pages 1587-1589Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1271/bbb.67.1587
Keywords
tyrosinase; resveratrol; stilbene; Dipterocarpaceae
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Stilbene derivatives, which are resveratrol (3,4',5-tri-hydroxy-trans-stilbene) oligomers ranging from monomer to tetramer, isolated from Dipterocarpaceae plants were tested for their inhibitory effects against murine tyrosinase activity. The structure-activity relationships obtained in this study suggest that the double bond in the stilbene skeleton is critical for the inhibition, and also that molecular size is important for inhibitory potency.
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