Journal
JOURNAL OF PEDIATRICS
Volume 143, Issue 1, Pages 127-129Publisher
MOSBY-ELSEVIER
DOI: 10.1016/S0022-3476(03)00212-9
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This report describes a boy with hyperimmunoglobulinemia D and periodic fever syndrome (HIDS). The serum IgD level was normal, but the serum IgA concentration was markedly elevated. In addition, he had a history of orchitis on two occasions, a previously unreported manifestation of HIDS. This report expands the clinical and laboratory features associated with HIDS and serves to emphasize that a normal serum IgD level does not exclude the diagnosis of HIDS.
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