4.8 Article

FootPrinter: a program designed for phylogenetic footprinting

Journal

NUCLEIC ACIDS RESEARCH
Volume 31, Issue 13, Pages 3840-3842

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkg606

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Funding

  1. NHGRI NIH HHS [R01 HG002602, HG02602-01] Funding Source: Medline

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Phylogenetic footprinting is a method for the discovery of regulatory elements in a set of homologous regulatory regions, usually collected from multiple species. It does so by identifying the best conserved motifs in those homologous regions. This note describes web software that has been designed specifically for this purpose, making use of the phylogenetic relationships among the homologous sequences in order to make more accurate predictions. The software is called FootPrinter and is available at http://bio.cs.washington.edu/software.html.

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