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Complex evolution and epidemiology of Dobrava-Belgrade hantavirus: definition of genotypes and their characteristics

Journal

ARCHIVES OF VIROLOGY
Volume 158, Issue 3, Pages 521-529

Publisher

SPRINGER WIEN
DOI: 10.1007/s00705-012-1514-5

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Funding

  1. Deutsche Forschungsgemeinschaft (Research Training Group 1121) [KR1293/9-1]
  2. European Commission (European Virus Archive, FP7 CAPACITIES project) [228292]
  3. Slovak Research and Development Agency [DO7RP-0008-09]
  4. Sigrid Juselius Foundation
  5. EU [FP7-261504]

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Dobrava-Belgrade virus (DOBV) is a human pathogen that has evolved in, and is hosted by, mice of several species of the genus Apodemus. We propose a subdivision of the species Dobrava-Belgrade virus into four related genotypes - Dobrava, Kurkino, Saaremaa, and Sochi - that show characteristic differences in their phylogeny, specific host reservoirs, geographical distribution, and pathogenicity for humans.

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