4.7 Review

The role of epoxide hydrolases in health and disease

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Characterization of Arachidonic Acid Metabolism by Rat Cytochrome P450 Enzymes: The Involvement of CYP1As

Ahmed A. El-Sherbeni et al.

DRUG METABOLISM AND DISPOSITION (2014)

Review Pharmacology & Pharmacy

Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health

Christophe Morisseau et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)

Review Biochemistry & Molecular Biology

Role of epoxide hydrolases in lipid metabolism

Christophe Morisseau

BIOCHIMIE (2013)

Article Biochemistry & Molecular Biology

Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity

Jonathan W. Nelson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

Patricia L. Podolin et al.

PROSTAGLANDINS & OTHER LIPID MEDIATORS (2013)

Article Oncology

EPHX1 A139G polymorphism and lung cancer risk: a meta-analysis

Hong Liu et al.

TUMOR BIOLOGY (2013)

Article Psychology, Clinical

EPHX1 Gene Polymorphisms in Alcohol Dependence and their Distribution among the Indian Populations

L. V. K. S. Bhaskar et al.

AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE (2013)

Article Biochemistry & Molecular Biology

Use of a Soluble Epoxide Hydrolase Inhibitor in Smoke-Induced Chronic Obstructive Pulmonary Disease

Lei Wang et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)

Article Medicine, General & Internal

Genetic Polymorphism of Microsomal Epoxide Hydrolase Enzyme Gene in Preeclamptic Females

Mennat Allah Kamal et al.

AMERICAN JOURNAL OF THE MEDICAL SCIENCES (2012)

Article Cardiac & Cardiovascular Systems

Homocysteine Upregulates Soluble Epoxide Hydrolase in Vascular Endothelium In Vitro and In Vivo

Donghong Zhang et al.

CIRCULATION RESEARCH (2012)

Article Biochemistry & Molecular Biology

EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides

Martina Decker et al.

JOURNAL OF LIPID RESEARCH (2012)

Article Chemistry, Medicinal

Discovery of Inhibitors of Soluble Epoxide Hydrolase: A Target with Multiple Potential Therapeutic Indications

Hong C. Shen et al.

JOURNAL OF MEDICINAL CHEMISTRY (2012)

Article Environmental Sciences

DNA DAMAGE AND SUSCEPTIBILITY ASSESSMENT IN INDUSTRIAL WORKERS EXPOSED TO STYRENE

Carla Costa et al.

JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2012)

Review Physiology

EPOXIDES AND SOLUBLE EPOXIDE HYDROLASE IN CARDIOVASCULAR PHYSIOLOGY

John D. Imig

PHYSIOLOGICAL REVIEWS (2012)

Article Biochemistry & Molecular Biology

The anti-inflammatory effects of soluble epoxide hydrolase inhibitors are independent of leukocyte recruitment

Benjamin B. Davis et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)

Article Pharmacology & Pharmacy

Activation of peroxisome proliferator-activated receptor-γ downregulates soluble epoxide hydrolase in cardiomyocytes

Wei Pang et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Inhibition of Soluble Epoxide Hydrolase Confers Cardioprotection and Prevents Cardiac Cytochrome P450 Induction by Benzo(a)pyrene

Mona E. Aboutabl et al.

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)

Article Biochemistry & Molecular Biology

Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase

Annette Cronin et al.

JOURNAL OF LIPID RESEARCH (2011)

Article Critical Care Medicine

Leukotriene A4 Hydrolase Inhibition Attenuates Allergic Airway Inflammation and Hyperresponsiveness

Navin L. Rao et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

Review Biochemistry & Molecular Biology

Epoxyeicosatrienoic Acid Analogs and Vascular Function

V. Sudhahar et al.

CURRENT MEDICINAL CHEMISTRY (2010)

Article Gastroenterology & Hepatology

Role of epoxide hydrolase 1 gene polymorphisms in esophageal cancer in a high-risk area in India

Rakhshan Ihsan et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2010)

Article Multidisciplinary Sciences

Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands

Philippe de Medina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Toxicology

Mammalian epoxide hydrolases in xenobiotic metabolism and signalling

Martina Decker et al.

ARCHIVES OF TOXICOLOGY (2009)

Article Chemistry, Medicinal

Structure-Based Optimization of Arylamides as Inhibitors of Soluble Epoxide Hydrolase

Anne B. Eldrup et al.

JOURNAL OF MEDICINAL CHEMISTRY (2009)

Article Chemistry, Medicinal

Development of metabolically stable inhibitors of mammalian microsomal epoxide hydrolase

Christophe Morisseau et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2008)

Article Endocrinology & Metabolism

Genetic analysis of the soluble epoxide hydrolase gene, EPHX2, in subclinical cardiovascular disease in the Diabetes Heart Study

Kathryn P. Burdon et al.

DIABETES & VASCULAR DISEASE RESEARCH (2008)

Article Food Science & Technology

Carcinogenicity study of 3-monochloropropane-1,2-diol in Sprague-Dawley rats

Wan-Seob Cho et al.

FOOD AND CHEMICAL TOXICOLOGY (2008)

Article Multidisciplinary Sciences

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

Bora Inceoglu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Genetic polymorphisms of GSTP1 and mEPHX correlate with oxidative stress markers and lung function in COPD

Arpana Vibhuti et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)

Article Dentistry, Oral Surgery & Medicine

Maternal smoking during early pregnancy, GSTP1 and EPHX1 variants, and risk of isolated orofacial clefts

Dorian Ramirez et al.

CLEFT PALATE-CRANIOFACIAL JOURNAL (2007)

Article Pharmacology & Pharmacy

Anandamide metabolism by human liver and kidney microsomal cytochrome P450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides

Natasha T. Snider et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Obstetrics & Gynecology

Association of microsomal epoxide hydrolase gene polymorphism and pre-eclampsia in Turkish women

Ergun Pinarbasi et al.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH (2007)

Article Multidisciplinary Sciences

Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors

Kara R. Schmelzer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Cell Biology

Cell-specific subcellular localization of soluble epoxide hydrolase in human tissues

AE Enayetallah et al.

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2006)

Article Multidisciplinary Sciences

Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor

KR Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Review Oncology

Leukotriene A4 hydrolase as a target for cancer prevention and therapy

X Chen et al.

CURRENT CANCER DRUG TARGETS (2004)

Article Obstetrics & Gynecology

Low-activity haplotype of the microsomal epoxide hydrolase gene is protective against placental abruption

S Toivonen et al.

JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION (2004)

Article Biochemistry & Molecular Biology

Breast cancer:: role of polymorphisms in biotransformation enzymes

J Sarmanová et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2004)

Article Biochemistry & Molecular Biology

Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase

P von Dippe et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Chemistry, Medicinal

Detoxication pathways involving glutathione and epoxide hydrolase in the in vitro metabolism of chloroprene

T Munter et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2003)

Article Pharmacology & Pharmacy

Polymorphisms in human soluble epoxide hydrolase

BD Przybyla-Zawislak et al.

MOLECULAR PHARMACOLOGY (2003)

Article Multidisciplinary Sciences

The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity

JW Newman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Pharmacology & Pharmacy

The telltale structures of epoxide hydrolases

M Arand et al.

DRUG METABOLISM REVIEWS (2003)

Article Biochemistry & Molecular Biology

Two exonic single nucleotide polymorphisms in the microsomal epoxide hydrolase gene are jointly associated with preeclampsia

J Laasanen et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2002)

Article Gastroenterology & Hepatology

Polymorphisms of microsomal epoxide hydrolase gene and severity of HCV-related liver disease

L Sonzogni et al.

HEPATOLOGY (2002)

Article Genetics & Heredity

A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia

PLM Zusterzeel et al.

JOURNAL OF MEDICAL GENETICS (2001)

Article Chemistry, Medicinal

Inhibition of microsomal epoxide hydrolases by ureas, amides, and amines

C Morisseau et al.

CHEMICAL RESEARCH IN TOXICOLOGY (2001)

Article Biochemistry & Molecular Biology

Crystal structure of human leukotriene A4 hydrolase, a bifunctional enzyme in inflammation

MMGM Thunnissen et al.

NATURE STRUCTURAL BIOLOGY (2001)

Article Biochemistry & Molecular Biology

Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation

CJ Sinal et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Review Biochemistry & Molecular Biology

Epoxide hydrolases: biochemistry and molecular biology

AJ Fretland et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2000)

Article Biochemistry & Molecular Biology

Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms

M Sandberg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Pathology

Metabolic detoxification: Implications for thresholds

F Oesch et al.

TOXICOLOGIC PATHOLOGY (2000)

Article Biochemistry & Molecular Biology

Identification of CYP2C9 as a human liver microsomal linoleic acid epoxygenase

AJ Draper et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)