4.7 Article

Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms

Related references

Note: Only part of the references are listed.
Article Gastroenterology & Hepatology

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

Jennifer E. Lambert et al.

GASTROENTEROLOGY (2014)

Article Biochemistry & Molecular Biology

Expression of Aldo-Keto Reductase Family 1 Member B10 in the Early Stages of Human Hepatocarcinogenesis

Hironori Tsuzura et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

Article Biochemistry & Molecular Biology

Role of Pregnane X Receptor in Obesity and Glucose Homeostasis in Male Mice

Krisstonia Spruiell et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Pharmacology & Pharmacy

Pregnane X Receptor Agonists Impair Postprandial Glucose Tolerance

J. Rysa et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)

Review Pharmacology & Pharmacy

PXR cross-talks with internal and external signals in physiological and pathophysiological responses

Susumu Kodama et al.

DRUG METABOLISM REVIEWS (2013)

Review Gastroenterology & Hepatology

Nuclear Receptors as New Perspective for the Management of Liver Diseases

Michael Trauner et al.

GASTROENTEROLOGY (2011)

Review Gastroenterology & Hepatology

Nuclear Receptors in Liver Disease

Martin Wagner et al.

HEPATOLOGY (2011)

Article Medicine, Research & Experimental

Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters

Romi Ghose et al.

LIFE SCIENCES (2011)

Review Pharmacology & Pharmacy

Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

Antonia H. Tolson et al.

ADVANCED DRUG DELIVERY REVIEWS (2010)

Article Biochemistry & Molecular Biology

Murine aldo-keto reductase family 1 subfamily B: identification of AKR1B8 as an ortholog of human AKR1B10

Amit Joshi et al.

BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

ChIPing the cistrome of PXR in mouse liver

Julia Yue Cui et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Biotechnology & Applied Microbiology

The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease

Silvia Sookoian et al.

PHARMACOGENETICS AND GENOMICS (2010)

Article Biochemistry & Molecular Biology

Lipid Droplets Finally Get a Little R-E-S-P-E-C-T

Robert V. Farese et al.

Article Gastroenterology & Hepatology

A Novel Pregnane X Receptor and S14-Mediated Lipogenic Pathway in Human Hepatocyte

Amelie Moreau et al.

HEPATOLOGY (2009)

Article Biochemistry & Molecular Biology

Aldo-keto Reductase Family 1 Member B10 Promotes Cell Survival by Regulating Lipid Synthesis and Eliminating Carbonyls

Chun Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Biochemistry & Molecular Biology

Hepatic Lipid Partitioning and Liver Damage in Nonalcoholic Fatty Liver Disease ROLE OF STEAROYL-CoA DESATURASE

Zheng Zheng Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Gastroenterology & Hepatology

Nonalcoholic Steatohepatitis Is Associated with Altered Hepatic MicroRNA Expression

Onpan Cheung et al.

HEPATOLOGY (2008)

Article Biochemistry & Molecular Biology

Post-transcriptional regulation of human pregnane x receptor by micro-RNA affects the expression of cytochrome P450 3A4

Shingo Takagi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Review Medicine, Research & Experimental

Nonalcoholic fatty liver disease: Pathogenesis and potential for nuclear receptors as therapeutic targets

Jacob George et al.

MOLECULAR PHARMACEUTICS (2008)

Review Pharmacology & Pharmacy

Molecular mechanisms and therapeutic targets in steatosis and steatohepatitis

Nora Anderson et al.

PHARMACOLOGICAL REVIEWS (2008)

Article Gastroenterology & Hepatology

Pregnane X receptor is essential for normal progression of liver regeneration

Guoli Dai et al.

HEPATOLOGY (2008)

Review Medicine, General & Internal

Nonalcoholic fatty liver disease as a complication of insulin resistance

Manal F. Abdelmalek et al.

MEDICAL CLINICS OF NORTH AMERICA (2007)

Article Biochemistry & Molecular Biology

Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver

Kouichi Nakamura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Pharmacology & Pharmacy

The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor

Changcheng Zhou et al.

MOLECULAR PHARMACOLOGY (2007)

Article Biochemistry & Molecular Biology

Insulin activates human sterol-regulatory-element-binding protein-1c (SREBP-1c) promoter through SRE motifs

Nicolas Dif et al.

BIOCHEMICAL JOURNAL (2006)

Article Biochemistry & Molecular Biology

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway

Jie Zhou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Review Gastroenterology & Hepatology

Mechanisms of disease: pathogenesis of nonalcoholic fatty liver disease

AJ Sanyal

NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY (2005)

Article Biochemistry & Molecular Biology

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine

O Burk et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin

A Geick et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)