Related references
Note: Only part of the references are listed.The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state
Ivan Kopljar et al.
JOURNAL OF GENERAL PHYSIOLOGY (2013)
Blockade of Kv1.3 Potassium Channels Inhibits Differentiation and Granzyme B Secretion of Human CD8+T Effector Memory Lymphocytes
Lina Hu et al.
PLOS ONE (2013)
Targeting Interleukin-4 in Asthma: Lost in Translation?
Tania Maes et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Effect of Gambierol and Its Tetracyclic and Heptacyclic Analogues in Cultured Cerebellar Neurons: A Structure-Activity Relationships Study
Sheila Perez et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
Functional Blockade of the Voltage-gated Potassium Channel Kv1.3 Mediates Reversion of T Effector to Central Memory Lymphocytes through SMAD3/p21cip1 Signaling
Lina Hu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Design and Synthesis of Skeletal Analogues of Gambierol: Attenuation of Amyloid-β and Tau Pathology with Voltage-Gated Potassium Channel and N-Methyl-D-aspartate Receptor Implications
Eva Alonso et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Vm24, a Natural Immunosuppressive Peptide, Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells
Zoltan Varga et al.
MOLECULAR PHARMACOLOGY (2012)
The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression
Jenny Lam et al.
DRUG DEVELOPMENT RESEARCH (2011)
Interleukin-13 Signaling and Its Role in Asthma
Efren L. Rael et al.
WORLD ALLERGY ORGANIZATION JOURNAL (2011)
Ion channels in T lymphocytes: An update on facts, mechanisms and therapeutic targeting in autoimmune diseases
Zoltan Varga et al.
IMMUNOLOGY LETTERS (2010)
The K+ channels KCa3.1 and Kv1.3 as novel targets for asthma therapy
Peter Bradding et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
4-Phenoxybutoxy-substituted heterocycles - A structure-activity relationship study of blockers of the lymphocyte potassium channel Kv1.3
Silke B. Bodendiek et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2009)
The functional network of ion channels in T lymphocytes
Michael D. Cahalan et al.
IMMUNOLOGICAL REVIEWS (2009)
Localization of Kv1.3 Channels in the Immunological Synapse Modulates the Calcium Response to Antigen Stimulation in T Lymphocytes
Stella A. Nicolaou et al.
JOURNAL OF IMMUNOLOGY (2009)
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Da Wei Huang et al.
NATURE PROTOCOLS (2009)
A polyether biotoxin binding site on the lipid-exposed face of the pore domain of Kv channels revealed by the marine toxin gambierol
Ivan Kopljar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels
Eva Cuypers et al.
TOXICON (2008)
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
Christine Beeton et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes
A Alfonso et al.
BIOCHEMICAL PHARMACOLOGY (2005)
K+ channels as targets for specific immunomodulation
KG Chandy et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2004)
Diverted total synthesis and biological evaluation of gambierol analogues: Elucidation of crucial structural elements for potent toxicity
H Fuwa et al.
CHEMISTRY-A EUROPEAN JOURNAL (2004)
Synthesis and biological evaluation of gambierol analogues
H Fuwa et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2003)
A novel fluorescent toxin to detect and investigate Kv1.3 channel up-regulation in chronically activated T lymphocytes
C Beeton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Total synthesis of (-)-gambierol
H Fuwa et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method
KJ Livak et al.
METHODS (2001)
Cascades of transcriptional induction during human lymphocyte activation
LW Ellisen et al.
EUROPEAN JOURNAL OF CELL BIOLOGY (2001)
Calcium-activated potassium channels sustain calcium signaling in T lymphocytes - Selective blockers and manipulated channel expression levels
CM Fanger et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Up-regulation of the IKCa1 potassium channel during T-cell activation -: Molecular mechanism and functional consequences
S Ghanshani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1:: A potential immunosuppressant
H Wulff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)