4.8 Article

Novel guanosine-cytidine dinucleoside that self-assembles into a trimeric supramolecule

Journal

ORGANIC LETTERS
Volume 5, Issue 15, Pages 2627-2630

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol034765y

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[GRAPHICS] Synthesis and assembly studies of a guanosine-cytidine dinucleoside 1 that self-assembles into a trimeric supramolecule (1) are presented. Dinucleoside 1 was obtained by utilizing two consecutive palladium-catalyzed cross-coupling reactions. Ensemble I was analyzed by ESI-MS, NMR spectroscoples, size exclusion chromatography (SEC), and vapor pressure osmometry (VPO).

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