Journal
PSYCHIATRY RESEARCH-NEUROIMAGING
Volume 123, Issue 3, Pages 207-211Publisher
ELSEVIER SCI IRELAND LTD
DOI: 10.1016/S0925-4927(03)00065-9
Keywords
single photon emission computed tomography; [I-123]beta-CIT; serotonin; brainstem; stroke
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Pathological crying (PC) is a neuropsychiatric disorder characterized by an excessive tendency towards crying after brain damage. To elucidate the role of serotonin neurotransmission for PC, a pilot study was performed using single photon emission computed tomography with [I-123]beta-CIT to estimate central (midbrain/pons and thalamus/hypothalamus) serotonin transporter (SERT) densities in 15 stroke patients who did or did not have PC. SERT binding ratios in midbrain/pons were significantly lower in the PC subgroup. (C) 2003 Elsevier Ireland Ltd. All rights reserved.
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