Journal
NATURE REVIEWS GENETICS
Volume 4, Issue 8, Pages 598-612Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg1124
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Funding
- Wellcome Trust [057559] Funding Source: Medline
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Until recently, the Y chromosome seemed to fulfil the role of juvenile delinquent among human chromosomes - rich in junk, poor in useful attributes, reluctant to socialize with its neighbours and with an inescapable tendency to degenerate. The availability of the near-complete chromosome sequence, plus many new polymorphisms, a highly resolved phylogeny and insights into its mutation processes, now provide new avenues for investigating human evolution. Y-chromosome research is growing up.
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