4.2 Article

One-pot synthesis of 2-alkyl/arylamino-4-oxo-4H-1-benzopyran-3-carboxaldehyde from 4-oxo-4H-1-benzopyran-3-carboxaldehyde

Journal

JOURNAL OF CHEMICAL RESEARCH
Volume -, Issue 8, Pages 459-460

Publisher

SAGE PUBLICATIONS LTD
DOI: 10.3184/030823403103174812

Keywords

1-benzopyran; nitrone; Zn-reduction; 3-formylchromone; quinoline

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Zn/NH4Cl-mediated reactions of aldehyde 1 with nitro compounds 2 afford 2-(N-alkyl/arylamino)-3-formylchromones 4, which on heating with 70% H2SO4 produces 9a-d and 11e-h from 4a-d and 4e-h, respectively.

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