4.3 Article

Cyclodextrin-enclosed substances of Brazilian propolis

Journal

CHEMICAL & PHARMACEUTICAL BULLETIN
Volume 51, Issue 8, Pages 984-985

Publisher

PHARMACEUTICAL SOC JAPAN
DOI: 10.1248/cpb.51.984

Keywords

Brazilian propolis; beta-cyclodextrin-inclusion; 4-hydroxycinnamic acid derivative

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By using beta-cyclodextrin-inclusion as a unique technique, an efficient separation of pharmacologically active phenolic compounds from Brazilian propolis was achieved to provide one new compound, 3-(3-hydroxy-3-methyl-butyl)-5-prenyl-4-hydroxycinnamic acid, together with two common cinnamic acid derivatives, artepillin C and capillartemisin A, and two known flavanols, aromadendrin and 3,5,7-trihydroxy-4'-methoxyflavanol.

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