Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 13, Issue 4, Pages 404-411Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/S0959-440X(03)00099-X
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Funding
- NIGMS NIH HHS [R01 GM060000, R01 GM060000-06A1, GM60000] Funding Source: Medline
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The beta-barrel membrane protein is found in the outer membranes of bacteria, mitochondria and chloroplasts. Approximately 2-3% of the genes in Gram-negative bacterial genomes encode beta-barrels. Whereas there are fewer than 20 known three-dimensional beta-barrel structures, genomic databases currently contain thousands of beta-barrels belonging to dozens of families. New research is revealing the variety of beta-barrel structures and the variety of functions performed by these versatile proteins.
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