Journal
CURRENT OPINION IN LIPIDOLOGY
Volume 14, Issue 4, Pages 347-352Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/00041433-200308000-00002
Keywords
inflammation; LDL; HDL; atherosclerosis; oxidized lipoproteins
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Lp-PLA(2) is an enzyme with potentially multiple risks in atherosclerosis. In humans the weight of evidence suggests that it is a positive risk factor for coronary heart disease - an observation commensurate with its position in the direct pathological sequence leading from formation of oxidized LDL in the artery wall to cellular dysfunction and formation of lesions.
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