Journal
TETRAHEDRON LETTERS
Volume 44, Issue 32, Pages 6161-6163Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/S0040-4039(03)01392-3
Keywords
trifluoromethylated amino alcohol; chiral ligand; enantioselective Reformatsky reaction
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The enantioselective Reformatsky reaction of PhCHO was achieved by the use of trifluoromethylated amino alcohols as chiral ligands to afford the corresponding optically active beta-hydroxy ester with up to 90% ee. (C) 2003 Elsevier Ltd. All rights reserved.
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