Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 68, Issue 16, Pages 6264-6267Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo034477f
Keywords
-
Categories
Ask authors/readers for more resources
The reaction of chiral sulfinimines 1c-g derived from aliphatic aldehydes with TMSCN in the presence of CsF gave alpha-amino nitriles in high diastereoselectivity and yield. alpha,beta-Diamino acid derivatives were also obtained in high diastereoselectivity from the reaction of 2-aziridinesulfinimines 1h and 1i followed by ring-opening of the products with thiophenol. The presence of hydrogen at the alpha-position of the C=N double bond is crucial in this TMSCN addition reaction.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available