Journal
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 1, Issue 16, Pages 2919-2921Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b305149h
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- NIGMS NIH HHS [GM-60261] Funding Source: Medline
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alpha,beta-Differentiated 1,2-vicinal diamines have been efficiently synthesized by using new electrophilic imidazolination reaction of alkenes. The hydrolysis of imidazolines was performed by treatment with 6 M HCl in THF at 70 degreesC without epimerization. Eight examples were examined to give good to excellent yields (87-96%).
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