Journal
NEUROLOGY
Volume 61, Issue 4, Pages 567-569Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.WNL.0000076477.71313.6E
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Funding
- NCRR NIH HHS [RR 00722] Funding Source: Medline
- NIAID NIH HHS [AI 35041, AI 35043, AI 35040, AI 35039, AI 35042] Funding Source: Medline
- NINDS NIH HHS [NS 26643] Funding Source: Medline
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The authors evaluated the association of a virologic response to highly active antiretroviral therapy, or a subsequent rebound, with performance on two measures of psychomotor speed in HIV-positive subjects. Virologic suppression was associated with improved performance on measures of psychomotor speed, and virologic rebound was associated with psychomotor speed performance decline. Changes in plasma HIV viral load in HIV-positive individuals with cognitive slowing correlate with performance on tests of psychomotor speed.
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