Journal
JOURNAL OF PHARMACY AND PHARMACOLOGY
Volume 55, Issue 9, Pages 1291-1297Publisher
OXFORD UNIV PRESS
DOI: 10.1211/0022357021693
Keywords
-
Categories
Ask authors/readers for more resources
Eight antioxidants from five different polyphenolic classes (cinnamic acids, benzoic acids, flavonoids, proanthocyanidins and stilbenes), and the water-soluble vitamin E derivative trolox were examined for their antioxidant activity in-vitro. In addition, the compounds were tested for their cytotoxicity on growing fibroblasts and their inhibition of the classical pathway of the complement system. Procyanidin C1 was shown to be a good scavenger of both DPPH. and HO., and a strong inhibitor of lipid peroxidation and the classical pathway of the complement system. Consequently, procyanidin C1 was classified as the most promising antioxidant in-vitro of all compounds tested. In contrast, genistein exhibited a very low antioxidant activity in both the lipid peroxidation and the DPPH. scavenging assay, a high cytotoxicity and a low complement-inhibiting activity.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available