Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 33, Issue 3, Pages 363-367Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-010-0303-5
Keywords
Alnus japonica; Betulaceae; Lupane triterpene; Anti-influenza; KBNP-0028
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Funding
- Ministry of Education, Science and Technology [2009-0093815]
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This study to identify anti-influenza components of the bark of Alnus japonica resulted in the isolation of four lupane-type triterpenes (1-4) and one steroid (5). Their structures were characterized on the basis of physicochemical properties, NMR evidence, and ESI-MS data compared with reported data in the literature. Betulinic aldehyde (3) exhibited a particularly strong anti-influenza effect against KBNP-0028 relative to a positive control.
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