Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 33, Issue 11, Pages 1729-1733Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-010-1103-7
Keywords
Deuteromycete; Marine derived fungus; Benzofuranoids A and B
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Two benzofuranoids, deuteromycol A, 6,7 dihydroxy 2 [1' hydroxy (1'-> 5 '') 2 '',3 '',4 '' trihydroxy 2 '',3 '' dihydropyran]benzofuran and deuteromycol B, 1 (6,7 dihydroxy benzofuran 2 yl)methyl acetate have been isolated from the ethanol extract of the marine derived fungal strain MF 003 (Deuteromycete) obtained from Red Sea mangrove drift wood Deuteromycols A and B contain a catecholic nucleus that to the best of our knowledge is unusual in association with marine fungi secondary metabolites Structures were established on the basis of extensive 1D and 2D NMR spectroscopic studies as well as on mass spectrometric analysis Besides, the extracts exhibited in vitro antibacterial activity
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