Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 33, Issue 5, Pages 647-654Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-010-0501-1
Keywords
Pyrimidines; Pyrazolines; Pyrans; Antimicrobial activity
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A number of new 2,6-didisubstituted pyrimidine, pyrazoline, and pyran derivatives were synthesized starting from their chalcone derivative. The synthesized compounds displayed different degrees of antimicrobial activity against Bscillus subtilis (Gram-positive), Pseudomonas aeruginosa (Gram-negative), and Streptomyces species (Actinomycetes).
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