4.6 Article

A new furofuran lignan from Isodon japonicus

Journal

ARCHIVES OF PHARMACAL RESEARCH
Volume 32, Issue 4, Pages 501-504

Publisher

PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-009-1404-x

Keywords

Isodon japonicus; Lamiaceae; Furofuran lignan; (-)-Sesamin-2,2'-diol

Funding

  1. Korean Ministry of Education, Science and Technology
  2. Korea Science and Engineering Foundation (KOSEF)
  3. Korea Government (MOST) [R13-2008-001-00000-00]

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A new sesamin type furofuran lignan, (-)-sesamin-2,2'-diol (1), along with two known flavonoids (2 and 3) and three phenolic compounds (4-6) were isolated from the aerial parts of Isodon japonicus. The structures of these compounds were determined by analysis of spectroscopic data (1D-, 2D-NMR, HRMS and CD) and by comparison of the data with those of related metabolites.

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