Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 32, Issue 2, Pages 191-194Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-009-1134-0
Keywords
Artocarpus elasticus; Flavonoids; Oxepinoflavone; Artoindonesianin E1; Cytotoxicity; P-388 cells
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Funding
- Endeavour Programme Australian Scholarships [519-2008]
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A new oxepinoflavone, artoindonesianin E1 (1), was isolated from the wood of Artocarpus elasticus, along with four known prenylated flavones: artocarpin (2), cycloartocarpin (3), cudraflavones A (4) and C (5). The structure of the new compound was identified by spectroscopic methods. Upon cytotoxic evaluation against murine leukemia P-388 cells, the new compound showed IC50 5.0 mu g/mL.
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