Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 31, Issue 9, Pages 1094-1097Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-001-1274-6
Keywords
Datura metel L.; psoriasis; solanaceae; chemical constituents
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Funding
- Major State Basic Research Development Program of China [2006CB504708]
- National Natural Science Foundation of China [30371736, 30672633]
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Phytochemical investigation of the 50% ethanol eluate fraction of macroporous resin for the flower of Datura metel L. led to the isolation of a new compound named yangjinhualine A (1) and five known megastigmane sesquiterpenes through repeated silica gel and ODS column chromatography and semipreparative HPLC. The structures of these compounds were determined by spectroscopic methods, including 2D-NMR, ESI-MS, and HR-ESI-MS spectrometry as well as by comparison with published data. Five known megastigmane sesquiterpenes were also isolated from D. metel L. for the first time.
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