Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 31, Issue 10, Pages 1241-1246Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-001-2102-5
Keywords
Microbial metabolism; 8-Prenylnaringenin
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Funding
- Korea Research Foundation
- Korean government (MOEHRD) [KRF-2005-041-E00488]
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Microbial metabolism studies of the phyto-estrogen (+/-)-8-prenylnaringenin (8-PN) (1) has led to the isolation of three pairs of metabolites (2-4). The structures of these compounds were identified as 5,4'-dihydroxy-7,8-[2-(1-hydroxy-1-methylethyl)-2,3-dihydrofurano]flavanones (2), 8-prenylnaringenin 7-O-beta-D-glucopyranosides (3), and 8-prenylnaringenin 7-O-beta-D-(6'-O-alpha-hydroxypropionyl)-glucopyranosides (4) on the basis of the spectroscopic analysis.
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