Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 31, Issue 8, Pages 970-972Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-001-1253-y
Keywords
Rhododendron spinuliferum; chromone; 3,5,7-trihydroxylchromone-3-O-alpha-L-arabinopyranoside; nitric oxide (NO) production
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Funding
- Changjiang Scholars and Innovative Research Team in University (PCSIRT)
- NCET Foundation
- NSFC [C03050201]
- National 863 Program [2006AA02Z338]
- Scientific Foundation of Shanghai China [07DZ 19728, 06DZ 19717, 06DZ 19005]
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A new chromone glycoside, 3,5,7-trihydroxylchromone-3-O-alpha-L-arabinopyranoside (1), together with quercetin (2), (+)-catechin (3), (-)-epi-catechin (4) were isolated from the aerial parts of Rhododendron spinulferum. The structure of 1 was elucidated on the basis of spectroscopic and 2D-NMR spectral analysis. In addition, 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.
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