Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 31, Issue 11, Pages 1477-1482Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-001-2133-y
Keywords
Polygonum hydropiper; Polygonaceae; Hidropiperoside A; Hidropiperoside B; Antioxidant
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By various chromatographic methods, two new phenylpropanoid esters of sucrose named hidropiperosides A (1) and B (2), and three known compounds as vanicosides A (3), B (4), and E (5) were isolated from the methanolic extract of the whole plant of Polygonum hydropiper L. (Polygonaceae). Their structures were elucidated by extensive spectroscopic methods including 1D- and 2D-NMR experiments, as well as ESI-MS analysis. All the isolated compounds were tested for their antioxidant activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay system. Among them, compounds 2 and 3 showed significant antioxidant activity with their SC50 values of 23.4 and 26.7 mu g/mL, respectively.
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